Isaac Newton, e.g Crossword Clue

Today's (6 August 2017) crossword provided to us by New York Times and the clue is "Isaac Newton, e.g".
The right answer or rather the best answer listed below:

Definition of "SIR"

used as a polite or respectful way of addressing a man, especially one in a position of authority

Example :

excuse me, sir

Dear Sir

 The Crossword clue "Isaac Newton, e.g" published 2 time/s & has 1 answer/s. 

Crossword	Date	Answer
New York Times	6 August 2017	SIR
L.A. Times Daily	26 July 2012	SIR